Apologies for multiple copies
=========================== Please note that the deadline for having special fare in hotels is the end of the year. After that date it could be difficult to find rooms in hotel due to high sky season in Rovereto. ============================
Computational Methods in Systems Biology (CMSB 2003) University of Trento 24-26 February, 2003 Rovereto, Italy http://www.unitn.it/convegni/cmsb.htm
Molecular biology has until now mainly focussed on individual molecules, on their properties as isolated entities or as complexes in very simple model systems. However, biological molecules in living systems participate in very complex networks, including regulatory networks for gene expression, intracellular metabolic networks and both intra- and intercellular communication networks. Such networks are involved in the maintenance (homeostasis) as well as the differentiation of cellular systems of which we have a very incomplete understanding. Nevertheless, the progress of molecular biology has made possible the detailed description of the components that constitute living systems, notably genes and proteins. Large scale genome sequencing means that we can (at least in principle) delimneate all macromolecular components of a given cellular system, and microarray experiments as well as large scale proteomics will soon give us large amounts of experimental data on gene regulation, molecular interactions and cellular networks. The challenge of the 21st century will be to understand how these individual components integrate to complex systems and the function and evolution of these systems, thus scaling up from molecular biology to systems biology. By combining experimental data with advanced formal theories from computer science, "the formal language for biological systems" to specify dynamic models of interacting molecular entities would be essential for 1. understanding normal behaviour of cellular processes, and how changes may affect the processes and cause disease. It may be possible to correlate genetic properties and symptoms in new and more efficient ways, based on an actual understanding of how various processes interact. 2. Providing predictability and flexibility to academic, pharmaceutical, biotechnology and medical researchers studying gene or protein functions. In particular, it may save time by reducing the number of experiments needed, if inadequate hypotheses could be excluded by computer simulation.
PARTICIPATION To participate please fill in the form at the URL http://www.unitn.it/convegni/cmsb_form.htm
The inscription fee is 200EURO until the end of this year and 250EURO for later registrations. The fee cover a copy of the proceedinngs, coffee break and lunches, the social dinnner and the special event.
Hotel reservation can be done at special fare by the end of the year according to the information that you find at the URL http://www.unitn.it/convegni/cmsb_hotels.htm
The programme is available at the web page of the workshop.
PROGRAMME COMMITTEE _ Charles Auffray, CNRS, Villejuif (F) _ Cosima Baldari, Università di Siena (I) _ Alexander Bockmayr, Université Henri Poincaré, Nancy (F) _ Luca Cardelli, Microsoft Research Cambridge (UK) _ Vincent Danos, Université Paris VII (F) _ Pierpaolo Degano, Università di Pisa (I) _ François Fages, INRIA Rocquencourt (F) _ Drabløs Finn, , Norwegian University of Science and Technology, Trondheim (N) _ Monika Heiner, Brandenburg University of Technology at Cottbus - (D) _ Ina Koch, University of Applied Sciences Berlin, (D). _ John E. Ladbury, University College London (UK) _ Patrick Lincoln, SRI (USA) _ Satoru Miyano, University of Tokyo (JP) _ Gordon Plotkin, University of Edinburgh (UK) _ Simon Plyte, Pharmacia Corporation (I) _ Corrado Priami (CHAIR), Università di Trento (I) _ Aviv Regev, Weizmann Institute of Science (IL) _ Magali Roux-Rouquié, BSMI Pasteur Institute (F) _ Vincent Schachter, Hybrigenics Paris (F) _ Masaru Tomita, Keio University (JP) _ Adelinde Uhrmacher, University of Rostock (D) _ Alfonso Valencia, CNB-CSIC Centro Nacional de Biotecnologia, Cantoblanco Madrid, (E) _ Olaf Wolkenhauer, UMIST, Manchester (UK)
ORGANIZING COMMITTEE
Linda Brodo, Michela de Concini, Corrado Priami, Debora Schuch da Rosa Machado
Organizing Secretariat Università degli studi di Trento Ufficio Manifestazioni e Convegni c/o Molino Vittoria, Via Verdi, 6 I-38100 Trento - Italy Tel. (0039) 0461-883215-16-25 Fax (0039) 0461-883222 e-mail: ufficio.convegni@amm.unitn.it
Proceedings The proceedings will be published in the Springer LNCS series and will be available at the workshop.
HOW TO REACH ROVERETO Airports The closest international airport to Rovereto is VERONA Valerio Catullo (in Villafranca). Other Airports: MILAN Linate or Malpensa, VENICE Marco Polo (in Tessera) ROME Da Vinci (in Fiumicino) is about 8 hours train journey from Rovereto.
Buses
There is a regular coach shuttle service every 20 minutes from Malpensa and Linate airports to Milano Central Station Malpensa - Milano Central Station about 50 minutes. every 20 minutes from 04.15 - 00.15 (see timetable on website) Linate - Milano connections City bus n.73
From the airport exit to town centre (piazza San Babila, Underground station): about 25 mins, departure every 10 min. Tickets ( 0.77 euro) on sale at news-stands. The 73 bus has special luggage racks.
By coach from the Central railway station There is a coach service between the Air Terminal at the Central Station and Linate airport. Departures every 20 mins. The 20 min. ride costs 2.58 Euro. Coaches have large baggage-holds. Linate Malpensa - Linate A coach shuttle connects both airports in c.75 mins. Tickets cost 9.29 euro.
From Verona Valerio Catullo airport to Verona Porta Nuova central train station about 15 minutes every 20 minutes from 6.10 - 23.30
Aereoporto Catullo: Connections Venice Marco Polo airport is about 30 minutes from Mestre train station by bus or you can take a vaporetto (taxi boat) to S. Lucia train station in Venice old city.
Trains
There is a bus shuttle service from all the airports to the nearest railway stations. You can check out the trains web site: www.trenitalia.com and click onto the British flag for train connections and times in English. Ask for "andata e ritorno" (return ticket) if you are going back to the same station, or "solo andata" (single). In big cities you will find someone who speaks English at the station but in small towns it is possible that they don't! Please note that trains marked ES (Euro Star), EC (Eurocity) or IC (Intercity) require a small supplement. The cheapest trains are Regionale (R) and Interregionale (IR). It is very important to remember to validate your ticket in one of the yellow machines on the platform before you get on the train. You will be fined if you forget!
Taxi
Taxis are available outside the railway station in Rovereto. Tel: 0464 421555/421 365